Publications

 

2013

 

 

  1. Nikhil Jain, Neha Vithani, Abu Rafay and Balaji Prakash$. Identification and characterization of a hitherto unknown nucleotide binding domain and an intricate inter-domain regulation in HflX, a ribosome binding GTPase. Nucleic Acids Research (2013) (in press). [International Peer reviewed – Oxford University Press].

 

  1. Pravin Kumar Ankush Jagtap, Sunil Kumar Verma, Neha Vithani, Vaibhav Bais and Balaji Prakash$. Crystal structures identify an atypical two-metal ion mechanism for uridyl transfer in  GlmU: Its significance to sugar nucleotidyl transferases. Journal of Molecular Biology. (2013), 425, 1745 -1759. [International Peer reviewed – Elsevier].

 

 

  1. Anand Baskaran, Soneya Majumdar and Balaji Prakash$. The Structural Basis Unifying Diverse GTP Hydrolysis Mechanisms. Biochemistry (2013) 52,1122-30. [International Peer reviewed – American Chemical Society].

 

  1. Megha Gulati, Nikhil Jain, Baskaran Anand, Balaji Prakash and Robert Britton$. Mutational analysis of the ribosome assembly GTPase RbgA provides insight into ribosome interaction and ribosome stimulated GTPase activation. Nucleic Acids Research (2013), 41, 3217–3227. [International Peer reviewed – Oxford University Press].

 

 

2012

 

 

  1. Pravin Kumar Ankush Jagtap, Vijay Soni, Neha Vithani, Gagan Deep Jhingan, Vaibhav Singh Bais, Vinay Kumar Nandicoori$, and Balaji Prakash$. Substrate bound crystal structures reveal features unique to Mycobacterium tuberculosis N-acetyl-glucosamine-1-phosphate uridyltransferase and a catalytic mechanism for acetyltransfer. Journal of Biological chemistry  (2012) 287, 39524-37. [International Peer reviewed – American Society for Biochemistry and Molecular Biology].

 

  1. Abu Rafay, Soneya Majumdar, and Balaji Prakash$. Exploring potassium-dependent GTP hydrolysis in TEES family GTPases. FEBS Open Bio  (2012) 2, 173-177. [International Peer reviewed – Elsevier].

 

  1. Sushil Kumar Tomar, Prashant Kumar, Soneya Majumdar, Varun Bhaskar, Prasun Dutta and Balaji Prakash$.  Extended C-terminus and length of the linker connecting the G-domains are species-specific variations in the EngA family of GTPases. FEBS Open Bio  (2012) 2, 191–195. [International Peer reviewed – Elsevier].

 

2011

 

 

  1. Sushil Kumar Tomar, Prashant Kumar, Balaji Prakash$. Deciphering the catalytic machinery in a universally conserved ribosome binding ATPase YchF, Biochem.Biophys. Res. Commun. (2011), 408, 459–464. [International Peer reviewed – Elsevier].

 

  1. Ashish Arora , Nagasuma R. Chandra , Amit Das , Balasubramanian Gopal , Shekhar C. Mande, Balaji Prakash, Ravishankar Ramachandran, Rajan Sankaranarayanan , K. Sekar , Kaza Suguna, Anil K. Tyagi , Mamannamana Vijayan. Structural biology of Mycobacterium tuberculosis proteins: The Indian efforts, Tuberculosis (2011), 91, 456-68. [International Peer reviewed – Elsevier].

 

 

 

2010

 

  1. Baskaran Anand, Parag Surana and Balaji Prakash$. Deciphering the Catalytic Machinery in 30S Ribosome Assembly GTPase YqeH. PloS ONE (2010), 5(4): e9944. doi:10.1371/journal.pone.0009944. [International Peer reviewed – Public Library of Science].

 

 

2009

 

  1. Divya Tiwari, Rajnish Kumar Singh, Kasturi Goswami, Sunil Kumar Verma, Balaji Prakash and Vinay Kumar Nandicoori. The N-terminal region of protein kinase G from Mycobacterium tuberculosis plays a regulatory role in modulating kinase activity and survival in the host macrophages. Journal of Biological Chemistry (2009) 284, 27467-79. [International Peer reviewed – American Society for Biochemistry and Molecular Biology].

 

  1. Baskaran  Anand, Parag  Surana, Sagar  Bhogaraju, Sushmita  Pahari and  Balaji Prakash$. Circularly permuted GTPase YqeH binds 30S ribosomal subunit:  Implications for its role in ribosome assembly. Biochem. Biophys. Res. Commun. (2009), 386, 602–606. [International Peer reviewed – Elsevier].

 

  1. Sunil Kumar Verma, Mamta Jaiswal, Neeraj Kumar, Amit Parikh, Vinay Kumar Nandicoori, Balaji Prakash$. Crystal structure of N-acetylglucosamine-1-phosphate uridyltransferase (GlmU) from Mycobacterium tuberculosis in a cubic space group. Acta Crystallographica. Section F. (2009) Struct Biol Cryst Commun. 2009, 65: 435–439. [International Peer reviewed – International Union of Crystallography].

 

  1. Sushil Kumar Tomar, Neha Dhimole, Moon Chatterji and Balaji Prakash$. Distinct GTP/GDP bound states of the tandem G-domains of Escherichia Coli EngA regulate ribosome binding.  Nucleic Acids Research (2009) 37(7):2359-70. [International Peer reviewed – Oxford University Press].

 

  1. Mathew Sajish, Sissy Kalayil, Sunil Kumar Verma, Vinay Kumar Nandicoori$ and Balaji Prakash$. The Significance of ExDD and RxKD Motifs Conservation in Rel Proteins. Journal of Biological Chemistry (2009), 284, 9115-9123. [International Peer reviewed – American Society for Biochemistry and Molecular Biology].

 

  1. Nikhil Jain, Neha Dhimole, Abu Rafay Khan, Debojyoti De, Sushil Kumar, Tomar, Mathew Sajish, Dipak Dutta, Pradeep Parrack and Balaji Prakash$.  E.coli HflX interacts with 50S ribosomal subunits in presence of nucleotides. Biochem. Biophys. Res. Commun. (2009), 379, 201-5. [International Peer reviewed – Elsevier].

 

  1. Amit Parikh*, Sunil Kumar Verma*, Shazia Khan, Balaji Prakash$ & Vinay Kumar Nandicoori$. PknB mediated phosphorylation of a novel substrate, N-acetylglucosamine-1-phosphate uridyltransferase (GlmU), modulates its acetyltransferase activity. Journal of Molecular Biology. (2009), 386, 451-64. [International Peer reviewed – Elsevier].

 

2007

 

18.  Mathew Sajish, Divya Tiwari, Dimple Rananaware, Vinay Kumar Nandicoori$ and Balaji Prakash$. A Charge Reversal Differentiates (p)ppGpp Synthesis by Monofunctional and Bifunctional Rel Proteins. Journal of Biological Chemistry. (2007) 282, 34977-34983.

 

2006

19.  Baskaran Anand, Sunil Kumar Verma, Balaji Prakash$ . Structural Stabilization of GTP binding domains in circularly permuted GTPases: Implications for RNA binding. Nucleic Acids Research. (2006) 34 , 2196-2205.

 

 

2005

20.  Rajeev Mishra, Sudheer Kumar Gara , Shambhavi Mishra, Balaji Prakash$ . Analysis of GTPases carrying hydrophobic amino acid substitutions in lieu of the catalytic glutamine: Implications for GTP hydrolysis. Proteins: Structure, Function, and Bioinformatics (2005) 59, 332-338.

 

 

From Post-Doctoral and Doctoral Work: 8.

 

2004

21.  Gerrit.J.K.Praefcke, Stephen Kloep, Utz Benscheid, Hanke Lilie , Balaji Prakash and Christian Herrmann. Identification of Residues in the Human Guanylate-binding Protein 1 Critical for Nucleotide Binding and Cooperative GTP Hydrolysis.   J. Mol. Biol. (2004) 344, 257-269.

 

2003

22.  Holger Rehmann *, Balaji Prakash * , Eva Wolf * , Alma Rueppel, Johan de Rooij, Johannes. L. Bos & Alfred Wittinghofer. Structure and Regulation of the cAMP binding domains of Epac2. Nature. Struct. Biol. (2003) 10, 26-32. Cover Article.

 

2000

23.  Balaji Prakash*, Louis Renault*, Gerrit.J.K.Praefcke, Christian Herrmann$ & Alfred Wittinghofer$.Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism. EMBO Journal (2000) 19, 4555-4564.

 

24.  Balaji Prakash*, Gerrit J.K.Praefcke*, Louis Renault, Alfred Wittinghofer$ & Christian Herrmann$. Structure of human Guanylate-binding protein-1 representing a class of GTP-binding proteins with unique properties. Nature (2000) 403, 567-571.

 

1997

25.  Balaji Prakash , M.R.N.Murthy$, Y N Sreerama, D Rajagopal Rao & Lalitha R Gowda$. Studies on simultaneous inhibition of trypsin and chymotrypsin by horsegram Bowman-Birk inhibitor. Journal of Biosciences (1997) 22 (5), 545-554.

 

26.  Balaji Prakash & M.R.N.Murthy$. Source and target enzyme signature in serine protease inhibitor active site sequences. Journal of Biosciences (1997) 22 (5), 555 -556 .

 

1996

27.  Balaji Prakash , S.Selvaraj, M.R.N.Murthy$, Y.N.Sreerama, D.Rajagopal Rao & L.R.Gowda. Analysis of amino acid sequences of Plant Bowman-Birk Inhibitors. Journal of Molecular Evolution. (1996) 42, 560-569.

 

1994

28.  Balaji Prakash , M.R.N.Murthy$, Y.N.Sreerama, P.R.Rama Sarma & D.Rajagopala Rao. Crystallization and preliminary X-ray diffraction studies on a Trypsin/Chymotrypsin double headed inhibitor from horse gram seeds. Journal of Molecular Biology. (1994) 235, 364-366.

 

(* refers to equal contributors, $ to corresponding author)