Research Interest

1. Synthetic Carbohydrate Chemistry of Biological Relevance (Glycosidase Inhibitors)

Glycosidase Inhibitors are extremely important from the point of view of controlling certain diseases. As a result, a lot of efforts are being made to design new glycosidase inhibitors based on mimicking transition state. In view of this, we have been involved in synthesising new inhibitors and also devise synthesis for known inhibitors. A few examples are:

Parasuraman Rajasekaran, Alafia A. Ansari, and Yashwant D. Vankar Eur. J. Org. Chem. 2015, 2902-2913

Rima Lahiri,, Ashokkumar Palanivel, Sudhir A. Kulkarni, and Yashwant D. Vankar  J. Org. Chem. 2014, 79, 10786−10800

Alafia A. Ansari and Yashwant D. Vankar J. Org. Chem., 2013, 78 , 9383-9395

Y. Suman Reddy, Pavan K Kancharla, Rashmi Roy and Yashwant D. Vankar Org. Biomol. Chem. 2012, 10, 276o

Preeti Gupta, A. P. John Pal, Y. Suman Reddy, Yashwant D. Vankar Eur. J. Org. Chem. 2011, 1166

A. P. John Pal, Preeti Gupta, Y. Suman Reddy and Yashwant D. Vankar Eur. J. Org. Chem. 2010, 6957

Hari Prasad Kokatla, Rima Lahiri, Pavan K. Kancharla, Venkata Ramana Doddi, Yashwant D. Vankar J. Org. Chem. 2010, 75, 4608

Nitee Kumari and Yashwant D. Vankar Org. Biomol. Chem. 2009, 7, 2104

M. Abrar Alam, Amit Kumar and Y. D. Vankar Eur. J. Org. Chem. 2008, 4972

D. V. Ramana and Y. D. Vankar Eur. J. Org. Chem. 2007, 5583

B. G. Reddy, Y. D. Vankar  Angew. Chem., Int. Ed. Engl. 2005, 44, 2001

K. Jayakanthan and Y. D. Vankar Organic Lett. 2005, 7, 5441

2. Functionalisation of carbohydrates leading to Glycosyl and Sugar Amino Acids, Amino Sugars and O- and C-Glycosides

Synthesis of glyocsyl and sugar amino acids for modulating various glycoproteins or glycopeptides is a vigorous activity. Likewise, synthesis of amino sugars, O- and C-glycosides via functionalistaion of monosaccharides is also an important area of research. Following represents part of our contribution in this direction:

Asadulla Mallick.,  Mallikharjunarao Y., Parasuraman R,  Roy R. and Yashwant D. Vankar Eur. J. Org. Chem. 2016, doi.org/10.1002/ejoc.201501245

Rashmi Roy, Ashok Kumar Palanivel, Asadulla Mallick and Yashwant D. Vankar Eur. J. Org. Chem. 2015, 4000-4005

Rashmi Roy, Parasuraman Rajasekaran, Asadulla Mallick, and Yashwant D. Vankar Eur. J. Org. Chem. 2014, 5564-5573

Suresh Dharuman and Yashwant D. Vankar Org. Lett. 2014, 16, 1172-1175

Y. Suman Reddy, Rima Lahiri, Yashwant D. Vankar Eur. J. Org. Chem. 2012, 4751-4761

Pavan K. Kancharla, Y. Suman Reddy, Suresh Dharuman, Yashwant D. Vankar J. Org. Chem. 2011, 76, 5832

Pavan K. Kancharla and Yashwant D. Vankar J. Org. Chem. 2010, 75, 8457

Preeti Gupta, Nitee Kumari, Aditi Agarwal and Y. D. Vankar Org. Biomol. Chem. 2008, 6, 3948-3956

G.K. Rawal, Amit Kumar, U. Tawar and Y. D. Vankar Org. Lett. 2007, 9, 5171

B. Gopal Reddy, K. P. Madhusudanan, Y. D. Vankar J. Org. Chem. 2004, 70, 2630.