• Shukla M, Chug, D and Ganesh S* (2024) Neuromuscular junction dysfunction in Lafora disease. Disease Models & Mechanisms, 17( 10): dmm050905. [PubMed] [Full Text] [Editor's Choice] [First Person Interview] [Cover Page Article] [Cover image highlighted on Biomedical Picture of the Day]
• Sen S, Ali R, Onkar A, Verma S, Ahmad QT, Bhadauriya P, Sinha P, Nair NN, Ganesh S and Verma S (2024) Synthesis of a highly thermostable insulin by phenylalanine conjugation at B29 Lysine. Communications Chemistry 7(1):161. [PubMed] [Full Text]
• Patil RP, Kumar N, Kaur A, Munian RK, Bhattacharya B, Ganesh S*, Parihar R*. (2024) Retinal vascular pathology in a mouse model of Lafora progressive myoclonus epilepsy. Neuroscience Research 204:58-63 [PubMed]
• Parihar R and Ganesh S* (2024) Lafora progressive myoclonus epilepsy: disease mechanism and therapeutic attempts. Journal of Biosciences 2024;49:22 [PubMed] [Full Text]

• Onkar A, Sheshadri D, Rai A, Gupta AK, Gupta N, and Ganesh S* (2023) Increase in brain glycogen levels ameliorates disease phenotype and rescues neurodegeneration in the Drosophila model of Huntington's disease. Disease Models & Mechanisms 16 (10): dmm050238 [PubMed] [Full Text] [First Person Interview] [Cover Page Article]
• Sen S, Ali R, Singh H, Onkar A, Bhadauria P, Ganesh S,  and Verma S (2023) Unnatural amino acid modified human insulin for visual monitoring of insulin aggregation. Organic & Biomolecular Chemistry 21 (37):7561-7566 [PubMed]

• Verma B, Sinha P, and Ganesh S* (2022) Ayurvedic formulations Amalaki Rasayana and Rasa Sindoor improve age-associated memory deficits in mice by modulating dendritic spine densities. Journal of Ayurveda and Integrative Medicine  13 (4): 100636 [PubMed]
• Sinha P, Verma B, and Ganesh S* (2022) Age-dependent reduction in the expression levels of genes involved in progressive myoclonus epilepsy correlates with increased neuroinflammation and seizure susceptibility in mouse models. Molecular Neurobiology  59 (9): 5532-5548 [PubMed]
• Joshi S, Agarwal S, Panjla A, Valiyaveettil S, Ganesh S, Verma S (2022) Inhibiting erastin-induced ferroptotic cell death by purine-based chelators. ChemBioChem. 23 (9): e202100654 [PubMed]
• Sen S, Ali R, Onkar A, Ganesh S, and Verma S (2022) Strategies for interference of insulin fibrillogenesis: challenges and advances. ChemBioChem 23 (11): e202100678. [PubMed]
• Gupta S, Singh V, Ganesh S, Singhal N, Sandhir R (2022) siRNA mediated GSK3beta knockdown targets insulin signalling pathway and rescues Alzheimer's disease pathology: Evidence from in vitro and in vivo studies. ACS Applied Materials & Interfaces 14 (1): 69-93 [PubMed]

• Sheshadri D, Onkar A, and Ganesh S* (2021)  Alterations in brain glycogen levels influence life-history traits and reduce the lifespan in female Drosophila melanogaster. Biology Open 10(12):bio059055 [PubMed]
• Bhadauriya P, Parihar R, Ganesh S* (2021)  Pesticides DEET, fipronil and maneb induce stress granule assembly and translation arrest in neuronal cells. Biochemistry and Biophysics Reports 28:101110 [PubMed]
• Sen S, Singh P, Mishra NK, Ganesh S, Sivakumar S, and Verma S (2021) Blended polar/nonpolar peptide conjugate interferes with human insulin amyloid-mediated cytotoxicity, Bioorganic Chemistry 111:104899. [PubMed]
• Lin A, Peiris NJ, Dhaliwal H, Hakim M, Li W, Ganesh S, Ramaswamy Y, Patel S, and Misra A (2021) Mural Cells: Potential Therapeutic Targets to Bridge Cardiovascular Disease and Neurodegeneration. Cells  10 (3): 593 [PubMed]
• Sinha P, Verma B, Ganesh S* (2021) Dexamethasone-induced activation of heat shock response ameliorates seizure susceptibility and neuroinflammation in mouse models of Lafora disease. Experimental Neurology 340:113656 [PubMed] [Cover Page Article]
• Taneja K and Ganesh S* (2021) Dendritic spine abnormalities correlate with behavioral and cognitive deficits in mouse models of Lafora disase. Journal of Comparative Neurology, 529(6):1099-1120 [PubMed]
• Sinha P, Verma B, Ganesh S* (2021)  Trehalose ameliorates seizure susceptibility in Lafora disease mouse models by suppressing neuroinflammation and endoplasmic reticulum stress. Molecular Neurobiology 58 (3): 1088-1101 [PubMed] [Full Text]

• Onkar A, Sheshadri D, Ganesh S* (2020) Glycogen: the missing link in neuronal autophagy? Autophagy 16(11):2102-2104 [PubMed]
• Agarwal S and Ganesh S* (2020) Perinuclear mitochondrial clustering, increased ROS Levels, and HIF1 are required for the activation of HSF1 by heat stress. Journal of Cell Science 133(13): jcs245589. [PubMed] [Highlights in the Issue].

• Singh V, Patel K, Sharma R, Patil P, Joshi A, Parihar R, Athilingam T, Sinha N, Ganesh S, Sinha P, Roy I, Thakur AK (2019) Discovery of arginine ethyl ester as polyglutamine aggregation inhibitor: Conformational transitioning of huntingtin N-terminus augments aggregation suppression. ACS Chemical Neuroscience 10 (9): 3969-3985. [PubMed]
• Rai A and Ganesh S* (2019)  Polyglucosan bodies in aged brain and neurodegeneration: cause or consequence? (Chapter 4) In Models, Molecules and Mechanisms in Biogerontology (Editor: Rath PC) Springer Nature Singapore Pte Ltd (pp 57-89).
• Kaur G, Kumari S, Saha P, Ali R, Patil S, Ganesh S, and Verma S (2019) Selective cell adhesion on a peptide-polymer electrospun fiber mats. ACS Omega  4 (2): 4376-4383 [PubMed]

• Goenka A, Parihar R, and Ganesh S* (2018) Heat shock-induced transcriptional and translational arrest in mammalian cells (Chapter in "Heat Shock Proteins and Stress") (Ed. Asea AAA, and Kaur P) Vol 15, Springer (pp 267-280).
• Bhat S and Ganesh S* (2018) New discoveries in progressive myoclonus epilepsies: a clinical outlook. Expert Review of Neurotherapeutics 18 (8): 649-667 [PubMed]
• Singh A,  Goenka A, Ganesh S, and Patra AK (2018) Luminescent Eu(III) and Tb(III) complexes containing dopamine neurotransmitter: biological interactions, antioxidant activity and cellular imaging studies.  European Journal of Inorganic Chemistry, 2018 (35): 3942-3951 [PubMed]
• Gupta S, Yadav K, Mantri SS, Singhal NK, Ganesh S and Sandhir R (2018) Evidence for compromised insulin signaling and neuronal vulnerability in an experimental model of sporadic Alzheimer's disease. Molecular Neurobiology 55 (12): 8916-8935 [PubMed]
• Ganesh S* (2018) Genetic pathways to neurodegeneration: Preface to Special Issue.  Journal of Genetics 97 (3): 587-588 [Full Text] [Special Issue Edited by S Ganesh]
• Parihar R, Rai A, and Ganesh S* (2018) Lafora disease: from genotype to phenotype, Journal of Genetics 97 (3): 611-624. [PubMed] [Full Text]
• Goenka A and Ganesh S* (2018) Role of long non-coding RNAs in cellular stress response. Proceedings of the Indian National Science Academy, 84 (2) 513-520 [PubMed] [Full Text]
• Saha P and Ganesh S*  (2018) Sex-biased transgenerational effect of maternal stress on neurodevelopment and cognitive functions. Journal of Genetics 97 (2):581-583 [PubMed] [Full Tex]
• Rai A, Singh PK, Singh V, Kumar V, Mishra R, Thakur AK, Mahadevan A, Shankar SK, Jana NR, and Ganesh S* (2018) Glycogen synthase protects neurons from cytotoxicity of mutant huntingtin by enhancing the autophagy flux. Cell Death & Disease 9: 201 [PubMed] [Full Text] [Article highlighted in FEBS J] [Media Coverage]

• Tomar K, Soni S, Bhadauriya P, Parihar R, Ganesh S, Nair NN, and Ramanathan G (2017) Mercuric ion sensing by overlapping beta-turn containing peptide. ChemistrySelect 2 (26): 8072-8075. [PubMed]
• Rai A, Mishra R, Ganesh S* (2017) Suppression of leptin signaling reduces polyglucosan inclusions and seizure susceptibility in a mouse model for Lafora disease. Human Molecular Genetics  26: 4778-4785 [PubMed] [Full Text]
• Upadhyay M, Agarwal S, Bhadauriya P, and Ganesh S* (2017) Loss of laforin or malin results in increased Drp1 level and concomitant mitochondrial fragmentation in Lafora disease mouse models. Neurobiology of Disease 100: 39-51 [PubMed].
• Jain N, Rai A, Mishra R and Ganesh S* (2017) Loss of malin, but not laforin, results in compromised autophagic flux and proteasomal dysfunction in cells exposed to heat shock. Cell Stress and Chaperones 22: 307-315. [PubMed]

• Parihar R, and Ganesh S* (2016) Autism genes: the continuum that connects us all. Journal of Genetics 95: 481-483. [PubMed] [Full Text]
• Goenka A, Sengupta S, Pandey R, Parihar R, Mohanta GC, Mukerji M, and Ganesh S* (2016) Human satellite-III non-coding RNAs modulate heat shock-induced transcriptional repression. Journal of Cell Science  129: 3541-3552 [PubMed] [Highlighted in the Issue] [Cover Page Article]
• Jain N, Mishra R, and Ganesh S* (2016) FoxO3a-mediated autophagy is down-regulated in laforin deficient mice, an animal model for Lafora progressive myoclonus epilepsy. Biochemical and Biophysical Research Communications 474: 321-327 [PubMed].
• Jain N, and Ganesh S* (2016) Emerging nexus between Rab GTPases, autophagy and neurodegeneration. Autophagy 12: 900-904 [PubMed]
• Upadhyay M, Bhadauriya P, and Ganesh S* (2016) Heat shock modulates the subcellular localization, stability, and activity of HIPK2. Biochemical and Biophysical Research Communications, 472: 580-584. [PubMed]
• Singh PK, and Ganesh S* (2016) Autophagy defects and Lafora disease (Chapter 10). In Autophagy (Volume 8: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging) (Ed: M.A. Hayat), Elsevier Inc.,  pp 188-197. [External Link]

• Mittal S, Upadhyay M, Singh PK, Parihar R, and Ganesh S* (2015) Interdependence of laforin and malin proteins for their stability and functions could underlie the molecular basis of locus heterogeneity in Lafora disease. Journal of Biosciences 40: 863-871. [PubMed] [Full Text]
• Upadhyay M, Gupta S, Bhadauriya P,  Ganesh S* (2015) Lafora disease proteins laforin and malin negatively regulate the HIPK2-p53 cell death pathway. Biochemical and Biophysical Research Communications 464: 106-111 [PubMed]

• Parihar R, Mishra R, Singh SK, Jayalakshmi S, Mehndiratta MM, Ganesh S* (2014) Association of the GRM4 gene variants with juvenile myoclonic epilepsy in an Indian population. Journal of Genetics 93: 193-197 [PubMed].
• Kumar, A, Singh PK, Parihar R, Dwivedi V, Lakhotia SC, and Ganesh S* (2014) Decreased O-linked GlcNAcylation protects from cytotoxicity mediated by huntingtin exon1 protein fragment. Journal of Biological Chemistry 289: 13543-13553 [PubMed]

• Singh PK, Singh S, and Ganesh S* (2013) Activation of serum/glucocorticoid-induced kinase 1 (SGK1) underlie increased glycogen levels, mTOR activation and autophagy defects in Lafora disease. Molecular Biology of the Cell 24: 3776-86 [PubMed]. [Discussed in NewsRx]
• Parihar R, and Ganesh S* (2013) The SCN1A gene variants and epileptic encephalopathies. Journal of Human Genetics 58: 573-80 [PubMed]

• Singh S, Singh PK, Bhadauriya P, and Ganesh S* (2012) Lafora disease E3 ubiquitin ligase malin is recruited to the processing bodies and regulates the microRNA-mediated gene silencing process via the decapping enzyme Dcp1a. RNA Biology 9: 1440-1449 [PubMed] [Full Text] [Article Highlighted in Mapping Ignorance].
• Chandrasekhar V, Das S, Yadav R, Hossain S, Parihar R, Ganesh S, and Sen P. (2012) Novel chemosensor for the visual detection of copper(II) in aqueous solution at the ppm level. Inorganic Chemistry 51:8664-8666. [PubMed]
• Klionsky DJ and 1269 others, including Ganesh S. (2012) Guidelines for  the use and  interpretation of  assays  for monitoring autophagy. Autophagy 8: 445-544. [PubMed]
• Serratosa JM, Minassian B, and Ganesh S (2012) Progressive myoclonus epilepsy of Lafora. In Jasper's Basic Mechanisms of the Epilepsies, 4th Edition (Eds: Noebels J, Avoli M, Rogawski M, Olsen R and Delgado-Escueta A), Oxford University Press, USA, pp 874-878. [PubMed] [NCBI Bookshelf]
• Singh S and Ganesh S. (2012) Phenotype variations in Lafora progressive myoclonus epilepsy: possible involvement of genetic modifiers? Journal of Human Genetics. 57: 283-285. [PubMed]
• Puri R, and Ganesh S*. (2012) Autophagy in Lafora disease: Cause or consequence? Autophagy 8, 289-290 [PubMed].
• Singh PK, Singh S and Ganesh S*. (2012) Laforin-malin complex negatively regulates glycogen synthesis by modulating the cellular glucose uptake via glucose transporters. Molecular and Cellular Biology 32: 652-663. [PubMed].
• Puri R, Suzuki T, Yamakawa K, and Ganesh S*. (2012) Dysfunctions in endosomal-lysosomal and autophagy pathways underlie neuropathology in a mouse model for Lafora disease. Human Molecular Genetics 21: 175-184. [PubMed] [Full Text]
• Dubey D, Parihar R, and Ganesh S*. (2012) Identification and characterization of novel splice variants of the human EPM2A gene mutated in Lafora progressive myoclonus epilepsy. Genomics, 99: 36-43. [PubMed]

• Puri R, Jain N, and Ganesh S*. (2011) Increased glucose concentration results in reduced proteasomal activity and the formation of glycogen positive aggresomal structures. FEBS Journal. 278, 3688-3698. [PubMed]
• Tripathi P, Awasthi S, Prasad R, Husain N, and Ganesh S (2011) Association of ADAM33 gene polymorphisms with asthma and its severity in Indian adult population. Journal of Genetics 90: 265-273. [PubMed]
• Siwach P, Parihar R, Sengupta S, and Ganesh S* (2011) Proline repeats, in cis and trans-positions, confer protection against the toxicity of misfolded proteins in a mammalian cellular model. Neuroscience Research 70: 435-441. [PubMed]
• Sengupta S, Badwar I, Upadhyay M, Singh S and Ganesh S* (2011) Malin and laforin are essential components of a protein complex that protects cells from the thermal stress. Journal of Cell Science 124: 2277-2286. [PubMed] [Full Text]
• Awasthi S, Tripathi P, Ganesh S, and Husain N (2011) Association of ADAM33 gene polymorphisms with asthma in Indian children. Journal of Human Genetics 56: 188-195. [PubMed].

• Puri R and Ganesh S* (2010) Laforin in autophagy: a possible link between carbohydrate and protein in Lafora disease? Autophagy 6: 1229-1231. [PubMed]
• Mittal S, and Ganesh S* (2010) Protein quality control mechanisms and neurodegenerative disorders: checks, balances and deadlocks. Neuroscience Research 68: 159-166. [PubMed] [Full Text] [Cover page article].
• Ganesh S* (2010). Juvenile myoclonic epilepsy: EFHC1 at the cross-roads? Annals of Neurosciences 17: 57-59. [PubMed] [Full Text].

• Puri R, Suzuki T, Yamakawa K, and Ganesh S* (2009) Hyperphosphorylation and aggregation of tau in laforin deficient mice, an animal model for Lafora disease. Journal of Biological Chemistry 284: 22657-22663. [PubMed] [Full Text]
• Sengupta S, Parihar R, and Ganesh S* (2009) Satellite III non-coding RNAs show distinct and stress-specific patterns of induction. Biochemical and Biophysical Research Communications 382, 102-107. [PubMed] [Full Text].
• Singh S, and Ganesh S* (2009) Lafora progressive myoclonus epilepsy: A meta-analysis of reported mutations in the first decade following the discovery of EPM2A and NHLRC1 genes. Human Mutation 30, 715-723. [PubMed] [Full Text]
• Siwach P, Sengupta S, Parihar R, and Ganesh S* (2009) Spatial positions of homopolymeric repeats in the human proteome and their effect on cellular toxicity. Biochemical and Biophysical Research Communications, 380, 382-386. [PubMed] [Full Text]
• Garyali P, Siwach P, Singh PK, Puri R, Mittal S, Sengupta S, Parihar R, and Ganesh S* (2009) The laforin-malin complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system. Human Molecular Genetics 18, 688-700 [PubMed] [Full Text].
• Banerjee I, Pandey U, Hasan OMT, Parihar R, Tripathi V, and Ganesh S* (2009) Association between inflammatory gene polymorphisms and coronary artery disease in an Indian population. Journal of Thrombosis and Thrombolysis 27, 88-94 [PubMed] [Full Text].
• Gour N, Purohit CS, Verma S, Puri R, Ganesh S (2009) Mannosylated self-assembled structures for molecular confinement and gene delivery applications. Biochemical and Biophysical Research Communications, 378, 503 - 506. [PubMed].

• Dubey D, and Ganesh S* (2008) Modulation of functional properties of laforin phosphatase by alternative splicing reveals a novel mechanism for the EPM2A gene in Lafora progressive myoclonus epilepsy. Human Molecular Genetics 17, 3010-3020. [PubMed] [Full Text]  [Article Highligted in Nature India Publication].
• Sengupta S and Ganesh S (2008) Noncoding RNAs in polyglutamine disorders: friend or foe? Journal of Biosciences 33, 303-306. [PubMed] [Full Text].
• Siwach P, and Ganesh S* (2008) Tandem repeats in human disorders: mechanism and evolution. Frontiers in Biosciences 13, 4467-4484 [PubMed].
• Singh S, Satishchandra P, Shankar SK, and Ganesh S* (2007) Lafora disease in Indian population: EPM2A and NHLRC1 gene mutations and their impact on subcellular localization of laforin and malin. Human Mutation 29, E1-E12 [PubMed] [Full Text].
• Banerjee I, Gupta V, Ahmed T, Faizaan M, Agarwal P, and Ganesh S* (2008) Inflammatory system gene polymorphism and the risk of stroke: a case-control study in an Indian population. Brain Research Bulletin , 75, 158-165. [PubMed] [Full Text]

• Mittal S, Dubey D, Yamakawa K, and Ganesh S* (2007) Lafora disease proteins malin and laforin are recruited to aggresomes in response to proteasomal impairment. Human Molecular Genetics 16, 753-762. [PubMed] [Full Text] [Cover page article].
• Banerjee I, Gupta V, and Ganesh S* (2007) Association of gene polymorphism with genetic susceptibility to stroke in Asian populations: a meta-analysis. Journal of Human Genetics 52, 205-219. [PubMed]

• Siwach P, Pophaly SD, and Ganesh S* (2006) Genomic and evolutionary insights into genes encoding proteins with single amino acid repeats. Molecular Biology and Evolution 23, 1357-1369. [PubMed] [Full Text]
• Singh S, Sethi I, Francheschetti S, Riggio C, Avanzini G, Yamakawa K, Delgado-Escueta AV, and Ganesh S* (2006) Novel NHLRC1 mutations and genotype-phenotype correlations in patients with Lafora's progressive myoclonus epilepsy. Journal of Medical Genetics 43, e48.  [PubMed] [Full Text]
• Ganesh S*, Puri R, Singh S, Mittal S, and Dubey D (2006) Recent advances in the molecular basis of Lafora's progressive myoclonus epilepsy. Journal of Human Genetics 51, 1-8. [PubMed]

• Ganesh S* and Singh S (2005) Neuronal survival in epilepsy: to die or not to die? Journal of Biosciences 30, 561-565. [PubMed]
• Ganesh S*, Tsurutani N, Amano K, Mittal S, Uchikawa C, Delgado-Escueta AV, and Yamakawa K (2005) Transcriptional profiling of a mouse model for Lafora disease reveals dysregulation of genes involved in the expression and modification of proteins. Neuroscience Letters 387, 62-67. [PubMed]
• Singh S, Suzuki T, Uchiyama A, Kumada S, Moriyama N, Hirose S, Takahashi Y, Inoue Y, Kimura K, Sawaishi S, Yamakawa K, and Ganesh S. (2005) Mutations in the NHLRC1 gene are the common cause for Lafora disease in the Japanese population. Journal of Human Genetics 50, 347-352. [PubMed]

• Suzuki T, Delgado-Escueta AV, Aguan K, Alonso ME, Shi J, Hara Y, Nishida M, Numata T, Medina MT, Takeuchi T, Morita R, Bai D, Ganesh S, Sugimoto Y, Inazawa J, Bailey JN, Ochoa A, Jara-Prado A, Rasmussen A, Ramos-Peek J, Cordova S, Rubio-Donnadieu F, Inoue Y, Osawa M, Kaneko S, Oguni H, Mori Y, Yamakawa K. (2004) Mutations in EFHC1 cause juvenile myoclonic epilepsy. Nature Genetics, 36(8):842-9 [PubMed]
• Ganesh S*, Tsurutani N, Suzuki T, Hoshii Y, Ishihara T, Deldago-Escueta AV, and Yamakawa K (2004) The carbohydrate-binding domain of Lafora disease protein targets Lafora polyglucosan bodies. Biochemical and Biophysical Research Communications 31, 1101-1109. [PubMed]

• Ganesh S*, Tsurutani N, Suzuki T, Ueda K, Agarwala KL, Osada H, Delgado-Escueta AV, and Yamakawa K (2003) The Lafora disease gene product laforin interacts with HIRIP5, a phylogenetically conserved protein containing a NifU-like domain. Human Molecular Genetics 12, 2359-2368. [PubMed]

• Delgado-Escueta AV, Perez-Gosiengfiao KB, Bai D, Bailey J, Medina MT, Morita R, Suzuki T, Ganesh S, Sugimoto Y, Yamakawa K, Ochao A, Jara Prado A, Rasmusse A, Ramos-Peek J, Cordava S, Rubio-Donnadieu F and Alonso ME (2003) Recent developments in the quest for myoclonic epilepsy genes. Epilepsia 44, 13-26. [PubMed]

• Ganesh S, Delgado-Escueta AV, Suzuki T, Francheschetti S, Riggio C, Avanzini G, Rabinowicz A, Bohlega S, Bailey J, Alonso ME, Rasmussen A, Ochoa A, Prado AJ, Medina MT, and Yamakawa K (2002) Genotype-phenotype correlations for EPM2A mutations in Lafora's progressive myoclonus epilepsy: Exon 1 mutations associate with an early onset cognitive deficit subphenotype. Human Molecular Genetics, 11: 1263-1271. [PubMed]
• Ganesh S, Delgado-Escueta AV, Avila MR, Sakamoto T, Machado-Salas J, Hoshii Y, Akagi T, Suzuki T, Amano K, Agarwala KL, Hasegawa Y, Ishihara T, Hashikawa T, Itohara S, Cornford EM, Niki H, Yamakawa K. (2002) Targeted disruption of Epm2a gene causes formation of Lafora inclusion bodies, neurodegeneration, ataxia, myoclonus epilepsy and impaired behavioral response in mice. Human Molecular Genetics, 11: 1251-1262. [PubMed]
• Sreenivasulu K, Ganesh S, and Raman R. (2002) Evolutionarily conserved, DMRT1, encodes alternatively spliced transcripts and shows dimorphic expression during gonadal differentiation in the lizard, Calotes versicolor. Mechansm of Development 119 (Suppll 1): S55-64.  [PubMed]
• Ganesh S, Suzuki T, and Yamakawa  K. (2002) Alternate splicing modulates subcellular localization of laforin. Biochemical and Biophysical Research Communications. 291: 1134-1137. [ PubMed